S3 Insulin action :
mTOR and insulin action
Friday 14 October 09:00~11:00 | Place: Convention hall C
Chairs: Sung Woo Park, Min ho Shong
    • The critical role of mTOR signaling in regulating metabolic stress has received intensive attention. In this session, new understandings of mTOR signaling in major insulin-sensitive tissues with a particular emphasis on its pathophysiologic relevance will be reviewed. Professor Yoon MS (Gachon Univ. Korea) will open the session by reviewing mTOR pathways to guide the audience. Professor Chen (UIUC, IL) will address multiple signaling pathways sensing amino acids upstream of mTOR for the regulation of myogenesis. Dr. Pajvani (Columbia University, NY) will show new data on the role of mTORC1-independent free Raptor on hepatic Akt activity and lipogenesis. Professor Han JW (Sungkyunkwan Univ. Korea) will present that S6K1 suppress Wnt gene expression and drive adipogenesis via epigenetic regulatory mechanisms after adipogenic stimulation.
Mee Sup Yoon Gachon University, Korea S3-1 Overview of mTOR signaling
Jie Chen University of Illinois, USA S3-2 mTOR signaling network in skeletal myogenesis
Utpal B. Pajvani Columbia University, USA S3-3 PHLPPs - necessary negative regulators of hepatic insulin signaling
Jeung-Whan Han Sungkyunkwan University, Korea S3-4 Control of adipogenesis by S6K1-mediated epigenetic modifications
S5 Islet biology & insulin secretion :
Toward beta cell replacement for diabetes
Friday 14 October 09:00~11:00 | Place: Emerald Hall B
Chairs: Sung-Hee Ihm , Ki-Ho Song
    • A decrease in the functional beta cell mass is the key feature of both type 1 and type 2 diabetes. Thus, recovery of functional beta cell mass is thought to be a possible therapeutic strategy to cure diabetes. Recently, technology to induce beta cell differentiation from stem cells is rapidly developing and will be the new source of beta cells for transplantation. In this session, four outstanding speakers will share their recent progress on beta cell differentiation from stem cells.
Metthias Hebrok University of California San Francisco, USA S5-1 Maturation of human embryonic stem cell derived beta cells
Ji Won Kim The Catholic University of Korea, Korea S5-2 Differentiation of human induced pluripotent stem cells into insulin-producing cells
Timothy Kieffer University of British Columbia, Canada S5-3 Making mature human islet cells from stem cells to model disease and treat diabetes
Yong-Mahn Han KAIST, Korea S5-4 Glucose responsiveness of islet-like organoids generated from human pluripotent stem cells
Quick Menu
Registration
Abstract
On-line submission
Venue
venue
Top