S4 Diabetic complications 1-Acute
Improving hypoglycemia in patients with diabetes
Friday 14 October 09:00~11:00 | Place: Emerald Hall A
Chairs: Min Young Chung , Hyun Shik Son
    • Hypoglycemia is recognized to be one of the strongest predictors of adverse clinical outcomes including macrovascular events and mortality in patients with diabetes; it is a major limiting factor in tight glycemic management of diabetes. At first in this session, Professor Daisuke Yabe (Kyoto University, Japan) will introduce safety issues of incretin therapy focused on hypoglycemia. For hypoglycemia-unawareness in type 1 diabetes, islet Transplantation and real-time continuous glucose monitoring will be discussed by Professors Kun-Ho Yoon (The Catholic University, Korea) and Sang-Man Jin (Sungkyunkwan University, Korea). In addition, neuronal damage associated with hypoglycemia will be dealt in depth by Professor Sang Won Suh (Hallym University, Korea).
Daisuke Yabe Kyoto University, Japan S4-1 Incretin therapy and hypoglycemia
Kun-Ho Yoon The Catholic University of Korea, Korea S4-2 Reversal of hypoglycemic unawareness with islet transplantation
Sang-Man Jin Sungkyunkwan University, Korea S4-3 Updates in real-time CGM and artificial pancreas
Sang Won Suh Hallym University, Korea S4-4 Prevention of hypoglycemia-induced neuronal death
S8 Diabetic complications 2-Chronic :
Novel experimental targets and therapeutic strategies
for diabetic vascular complications
Friday 14 October 16:00~18:00 | Place: Emerald Hall A
Chairs: Dong-Seop Choi, Ki-Up Lee
    • This session will focus on the new experimental and therapeutic strategies for preventing and treating diabetic vascular complications. Prof. Susztak from University of Pennsylvania will summarize her basic research and genomic and epigenomic studies. She will also provide next generation therapeutics for chronic kidney disease. Prof. Miyata from Tohoku University will present his recent discovery about new PAI-1 inhibitor to retard diabetic vascular complications as well as aging. Prof. Hyo-Soo Kim in Seoul National University will talk about Notch signaling, which is a new pathophysiologic mechanism in diabetic microvascular complications. Finally, Prof. Jeong Hun Kim from Seoul National University will raise concerns related anti-VEGF antibody treatment in diabetic retinopathy and provide some recent results to overcome them, such as targeting HIFs.
Katalin Susztak University of Pennsylvania, USA S8-1 Diabetic kidney disease; past, present and future
Toshio Miyata Tohoku University, Japan S8-2 Discovery and development of PAI-1 inhibitors: potential clinical implications
Hyo-Soo Kim Seoul National University, Korea S8-3 Mechanism of diabetic microvasculopathy, high jagged1 and low notch
Jeong Hun Kim Seoul National University, Korea S8-4 A toe in the door of translational research on diabetic retinopathy
S14 Diabetic complications 3-Chronic :
Deciphering diabetic complications one piece at a time
Saturday 15 October 14:00~16:00 | Place: Emerald Hall A
Chairs: Joong Yeol Park, Jaetaek Kim
    • Diabetes dramatically increases the risk of various cardiovascular complications, including coronary artery disease, stroke, and atherosclerosis. In this session, four prominent researchers will give lectures about recent advances in diabetes-associated nervous and cardiovascular consequences. Professor Seong-Su Moon, from Dongguk University, will present recent advances focused on the brain and diabetic neuropathy. Professor Eun Ho Choo, from The Catholic University of Korea, will focus on the extent and severity of coronary atherosclerosis in asymptomatic diabetic individuals evaluated by coronary CT angiography. Professor Adam R. Wende, from University of Alabama at Birmingham, will present emerging evidence for epigenetic transcriptional regulation in diabetic cardiomyopathy. Professor Seungjoo Lee, from department of neurosurgery in University of Ulsan, will deliver a lecture on the mechanism by which the endothelium-specific transcription factor Sox17 regulates vascular homeostasis.
Seong-Su Moon Dongguk University, Korea S14-1 Diabetic neuropathy in brain: time for a paradigm shift
Eun Ho Choo The Catholic University of Korea, Korea S14-2 Extent & severity of coronary atherosclerosis in asymptomatic diabetic individuals
Adam R. Wende University of Alabama at Birmingham, USA S14-3 My sweetheart is broken: role of glucose in diabetic cardiomyopathy
Seung Joo Lee University of Ulsan, Korea S14-4 Deficiency of endothelial transcription factor Sox17 causes intracranial aneurysm
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